Women across the world are disproportionately affected by the COVID-19 pandemic, reversing gains in gender equality made in recent decades. Women-led businesses have been more negatively impacted economically, especially in sectors hardest hit by the pandemic. The G20 must take urgent actions to promote gender equality by economically empowering women-led businesses in the post-COVID world. Public-private sector schemes that accelerate technology adoption, innovation and digital skills training for women entrepreneurs and strengthen financing and fiscal assistance for women-led businesses should be actively supported and encouraged.